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The lymphocyte/monocyte ratio predicts the efficacy of isatuximab plus pomalidomide in multiple myeloma patients.

Yutaka ShimazuJunya KandaYoshiyuki OndaShin-Ichi FuchidaKensuke OhtaYuji ShimuraSatoru KosugiRyosuke YamamuraMitsuhiro MatsudaHitoshi HanamotoYoko AdachiNaoyuki AnzaiMasaaki HottaKentaro FukushimaHideo YagiSatoshi YoshiharaYasuhiro TanakaTeruhito TakakuwaHirokazu TanakaHirohiko ShibayamaNobuhiko UoshimaNaoki HosenTomoki ItoChihiro ShimazakiItaru MatsumuraJunya KurodaAkifumi Takaori-KondoMasayuki Hino
Published in: Cancer immunology, immunotherapy : CII (2024)
We found that the patients with higher LMR (≥ 4) could obtain longer PFS and OS under the Isa-PD regimen. Other cohort studies of isatuximab treatment might be necessary to substantiate our results.
Keyphrases
  • multiple myeloma
  • ejection fraction
  • newly diagnosed
  • peripheral blood
  • dendritic cells
  • prognostic factors
  • endothelial cells
  • patient reported
  • replacement therapy