Early molecular biomarkers predicting the evolution of allergic rhinitis and its comorbidities: A longitudinal multicenter study of a patient cohort.
Francesca CiprianiSalvatore TripodiValentina PanettaSerena PernaEkaterina PotapovaArianna DondiRoberto BernardiniCarlo CaffarelliAntonella CasaniRosa CervoneLoredana ChiniPasquale ComberiatiGiovanna De CastroMichele Miraglia Del GiudiceIride Dello IaconoAndrea Di Rienzo BusincoMarcella GallucciArianna GiannettiCarla MastrorilliViviana MoscheseSimone PelosiIfigenia SfikaElena VarinValeria VillellaAnna Maria ZicariGiulia BrindisiGiampaolo RicciPaolo Maria Matricardinull nullPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2019)
Seasonal allergic rhinoconjunctivitis is clinically heterogeneous in its evolution from childhood to adolescence. The detection of serum IgE to specific molecules (Phl p 1, Phl p 5, Bet v 1, Pru p 3) may be useful as biomarkers to predict SAR persistence and future onset of comorbidities, such as asthma and/or OAS.