Liver stiffness accuracy by MR elastography in histologically proven non-alcoholic fatty liver disease patients: a Spanish cohort.

Carmen Lara RomeroJia-Xu LiangIsabel Fernández LizaranzazuJavier AmpueroJavier CastellCarmen Del Prado AlbaInmaculada Domínguez PascualManuel Romero

Published in: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva (2022)

MRE is an effective and non-invasive method for detecting and staging liver fibrosis in NAFLD patients. MRE is more accurate than transient elastography and allows the study of liver anatomy. Histological inflammation and surrogate biomarkers of inflammation can overestimate liver stiffness, but only GGT was statistically significant in the multivariate analysis. Important features of NAFLD patients such as obesity, Mellitus diabetes, or lipidic profile did not affect MRE accuracy.

Keyphrases

end stage renal disease
liver fibrosis
ejection fraction
newly diagnosed
chronic kidney disease
oxidative stress
prognostic factors
metabolic syndrome
insulin resistance
weight loss
computed tomography
high resolution
body mass index
patient reported outcomes
skeletal muscle
high fat diet induced
contrast enhanced