Vitamin D and Calcium Supplementation Accelerate Vascular Calcification in a Model of Pseudoxanthoma Elasticum.

Elise BouderliqueEllie TangJeremy ZaworskiAmélie CoudertDominique Bazin Ferenc Borondics Jean-Philippe HaymannGeorges LeftheriotisLudovic MartinMichel DaudonEmmanuel Letavernier

Published in: International journal of molecular sciences (2022)

vitamin D and/or calcium supplementation accelerate vascular calcification in a murine model of PXE. These results sound a warning regarding the use of these supplementations in PXE patients and, to a larger extent, patients with low systemic pyrophosphate levels.

Keyphrases

end stage renal disease
chronic kidney disease
newly diagnosed
ejection fraction
prognostic factors
patient reported outcomes
drug induced