Predictive Performance of Published Tacrolimus Population Pharmacokinetic Models in Thai Kidney Transplant Patients.

Janthima MethaneethornManupat LohitnavyKamonwan OnlamaiNattawut Leelakanok

Published in: European journal of drug metabolism and pharmacokinetics (2021)

We evaluated ten tacrolimus PopPK models, and eight models resulted in satisfactorily individual predicted tacrolimus concentrations in Thai kidney transplant patients and may be used to aid tacrolimus dose adjustment along with a clinical judgment.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
patient reported outcomes