Comprehensive degradation profiling and influence of different oxidizing reagents on tinoridine hydrochloride: Structural characterization of its degradation products using HPLC and HRMS.
Vivek DhimanKanchan PatilLaximan VelipM V N Kumar TalluriGananadhamu SamanthulaPublished in: Rapid communications in mass spectrometry : RCM (2021)
Stress study was successfully carried out as per ICH Q1A (R2) guideline on tinoridine hydrochloride. A total of six new degradation products were characterized, DP 2 and DP 6 formed by the effect of co-solvent. This study provides the scientifically sound basis for quality monitoring and storage conditions of tinoridine hydrochloride.
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