Circulating plasma MicroRNA in patients with active acromegaly.
Alexander LutsenkoZhanna BelayaAlexey NikitinAlexander SolodovnikovAnastasia LapshinaPhilipp KoshkinMaria VorontsovaLiudmila RozhinskayaGalina MelnichenkoIvan DedovPublished in: The Journal of clinical endocrinology and metabolism (2021)
In a two-phase experiment using two different techniques we found and validated the downregulation of plasma miR-4446-3p and miR-215-5p in patients with acromegaly compared to healthy subjects, which makes them promising biomarkers for further research.