Quantifying Adaptive and Innate Immune Responses in HIV-Infected Participants Using a Novel High Throughput Assay.

Michelle K YongPaul U CameronTim SpelmanJulian H ElliottChristopher K FairleyJeffrey BoyleMisato MiyamasuSharon R Lewin

Published in: PloS one (2016)

Using a high throughput assay which assesses both adaptive and innate immune function, we showed elevated IFN-γ production in HIV-infected patients both on and off ART. Further research is warranted to determine if changes in QuantiFERON Monitor® are associated with clinical outcomes.

Keyphrases

innate immune
high throughput
antiretroviral therapy
hiv infected patients
hiv infected
human immunodeficiency virus
single cell
immune response