Submicromolar copper (II) ions stimulate transretinal signaling in the isolated retina from wild type but not from Cav2.3-deficient mice.

Jan Niklas LükeFelix NeumaierSerdar AlpdoganJürgen HeschelerToni SchneiderWalid AlbannaIsha Akhtar-Schäfer

Published in: BMC ophthalmology (2020)

Cu2+-dependent modulation of transretinal signaling only occurs in the murine retina from Cav2.3 competent mice, supporting the ideas derived from previous work in the bovine retina that R-type Ca2+ channels are involved in shaping transretinal responses during light perception.

Keyphrases

wild type
diabetic retinopathy
optic nerve
high fat diet induced
type diabetes
metabolic syndrome
protein kinase
oxide nanoparticles