Antibodies Against ZSCAN1 in Pediatric and Adult Patients With Non-Paraneoplastic ROHHAD Syndrome.
Ana Beatriz SerafimGemma Olivé-CireraÁngel Ortega-GonzálezMichael C KruerDebra E Weese-MayerCasey M RandCarmen FonsJoaquín Alejandro Fernández-RamosMaria ClementeMateus Mistieri SimabukuroEmilia Katiane EmbiruçuSalvador Ibáñez-MicóJosep O DalmauFrancesc GrausThaís ArmangueLidia SabaterPublished in: Neurology(R) neuroimmunology & neuroinflammation (2024)
Patients with ROHHAD syndrome should be investigated for the presence of ZSCAN1-abs in CSF. The antibodies do not necessarily predict the presence of a tumor. The detection of ZSCAN1-abs in an adult patient suggests that this condition also occurs beyond the pediatric age.