Login / Signup

Hypersensitivity reactions to vaccines in children: from measles to SARS-CoV-2.

Carlo CaffarelliLucia LiottiAnnamaria BianchiPaolo BottauSilvia CaimmiGiuseppe CrisafulliFabrizio FranceschiniClaudia PaglialungaFrancesca SarettaFrancesca Mori
Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2022)
Allergic individuals at risk for hypersensitivity reactions to measles vaccine marketed for a long time are well established. On the other hand, risk factors for hypersensitivity reactions to the new mRNA COVID-19 vaccines currently include a history of allergy, allergy to excipient of the vaccine, or hypersensitivity reactions to the first dose of COVID-19 vaccine. In the last two cases, the recipient should be assessed by an allergist before vaccination to share a decision on the choice of vaccination. Studies on skin testing accuracy and desensitization protocols to the COVID-19 vaccines and the efficacy of potential alternatives in patients with confirmed hypersensitivity reactions to the first COVID-19 vaccine are necessary to improve the safety of COVID-19 vaccines.
Keyphrases
  • sars cov
  • coronavirus disease
  • respiratory syndrome coronavirus
  • drug induced
  • young adults
  • risk assessment
  • atopic dermatitis
  • climate change
  • human health