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Recommendations for genetic testing to reduce the incidence of anthracycline-induced cardiotoxicity.

Folefac AminkengColin J D RossShahrad R RassekhSoomi HwangMichael J RiederAmit P BhavsarAnne SmithShubhayan SanataniKaren A GelmonDaniel BernsteinMichael R HaydenUrsula AmstutzBruce C Carletonnull null
Published in: British journal of clinical pharmacology (2016)
Existing evidence demonstrates that genetic factors have the potential to improve the discrimination between individuals at higher and lower risk of ACT. Genetic testing may therefore support both patient care decisions and evidence development for an improved prevention of ACT.
Keyphrases
  • high glucose
  • risk factors
  • diabetic rats
  • clinical practice
  • copy number
  • drug induced
  • risk assessment
  • endothelial cells
  • dna methylation
  • climate change