Genomic profiling of small bowel adenocarcinoma: a pooled analysis from 3 databases.

Thomas AparicioJulie HenriquesMagali SvrcekAziz ZaananSylvain ManfrediStefano Cascinu David TougeronJean-Marc GornetMarine JaryEric TerrebonneGuillaume PiessenPauline AfchainCédric LecailleMarc PocardThierry LecomteMargherita RiminiFrédéric Di FioreValérie Le Brun LyStefano CascinuDewi VernereyPierre Laurent-Puig

Published in: British journal of cancer (2024)

There is a different genomic profile according to the stage and predisposing disease. dMMR and APC mutation in localized tumour predict a better prognosis.

Keyphrases

small bowel
copy number
squamous cell carcinoma
single cell
big data
gene expression
radiation therapy
dna methylation
machine learning
rectal cancer