Login / Signup

Organ-specific immune response in lethal SARS-CoV-2 infection by deep spatial phenotyping.

Akhila BalachanderBernett LeeSubhra K BiswasDavid C LyeRaymond Tp LinYee-Sin LeoPaul ChuiLisa Fp NgLaurent Renia
Published in: Clinical & translational immunology (2022)
With resurgence of infection in younger populations, single-cell cytokine localisation in immune and stromal structures provides important mechanistic insights into organ-specific immunopathology of naïve SARS-CoV-2 infection in the absence of other comorbidities.
Keyphrases
  • immune response
  • single cell
  • high throughput
  • respiratory syndrome coronavirus
  • rna seq
  • bone marrow
  • high resolution
  • mass spectrometry
  • inflammatory response