Organ-specific immune response in lethal SARS-CoV-2 infection by deep spatial phenotyping.
Akhila BalachanderBernett LeeSubhra K BiswasDavid C LyeRaymond Tp LinYee-Sin LeoPaul ChuiLisa Fp NgLaurent ReniaPublished in: Clinical & translational immunology (2022)
With resurgence of infection in younger populations, single-cell cytokine localisation in immune and stromal structures provides important mechanistic insights into organ-specific immunopathology of naïve SARS-CoV-2 infection in the absence of other comorbidities.