Visceral obesity and sarcopenia as predictors of efficacy and hematological toxicity in patients with metastatic breast cancer treated with CDK 4/6 inhibitors.

Kadriye Bir Yücel Uguray Aydos Osman Sütçüoğlu Atiye Cenay Karabörk Kilic Nuriye Ozdemir Ahmet Özet Ozan Yazıcı

Published in: Cancer chemotherapy and pharmacology (2024)

The present study supported the significance of sarcopenia and low visceral adipose tissue as potential early indicators of poor PFS in patients treated with CDK 4/6 inhibitors.

Keyphrases

insulin resistance
metastatic breast cancer
adipose tissue
skeletal muscle
cell cycle
metabolic syndrome
high fat diet
type diabetes
high fat diet induced
oxidative stress
weight loss
cell proliferation
weight gain
physical activity
risk assessment
human health