Serum microRNA-146a-5p and microRNA-221-3p as potential clinical biomarkers for papillary thyroid carcinoma.

Antonella VerrientiValeria PecceGiorgio GraniValeria Del GattoSamuele BarpMarianna MaranghiLaura GiacomelliCira Di GioiaMarco BiffoniSebastiano FilettiCosimo DuranteMarialuisa Sponziello

Published in: Journal of endocrinological investigation (2024)

MiRNA-146a-5p and miRNA-221-3p, particularly the former, could be valuable diagnostic biomarkers for PTCs. They also seem to be effective in monitoring disease progression during patient follow-up by evaluating their fold change, even when thyroglobulin is uninformative.

Keyphrases

lymph node
lymph node metastasis
case report
risk assessment
human health
climate change