P53 Gene Expression and Nitric Oxide Levels after Artemisinin-Caffeine Treatment in Breast, Lungs and Liver of DMBA-Induced Tumorigenesis.

Titilope Modupe DokunmuSandra C OparaNgozi Awa ImagaOmiete U AwaniDavid O EnomaBababode I Adelani

Published in: Asian Pacific journal of cancer prevention : APJCP (2023)

This study shows a dose-dependent synergistic anticancer effects of caffeine and artemisinin combination on p53 gene and nitric oxide regulation hence can mitigate tumor development.

Keyphrases

nitric oxide
gene expression
nitric oxide synthase
plasmodium falciparum
hydrogen peroxide
dna methylation
high glucose
diabetic rats
copy number
cancer therapy
endothelial cells
genome wide identification