Multivariate estimation of factor structures of complex traits using SNP-based genomic relationships.

Ronald de VlamingEric A W SlobPatrick J F GroenenCornelius A Rietveld

Published in: BMC bioinformatics (2022)

MGREML can now be used to estimate multivariate factor structures and perform inferences on such factor models at low computational cost. This new feature enables simple structural equation modeling using MGREML, allowing researchers to specify, estimate, and compare genetic factor models of their choosing using SNP data.

Keyphrases

genome wide
high resolution
copy number
machine learning
dna methylation