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Identification of four compounds from the Pharmakon library with antifungal activity against Candida auris and species of Cryptococcus.

Haroldo Cesar de OliveiraRafael F CastelliLysangela R AlvesJoshua D NosanchukEhab A SalamaMohamed SeleemMarcio Lourenço Rodrigues
Published in: Medical mycology (2022)
Fungal infections can be lethal and the options to fight them are scarce. We tested 1600 molecules for their ability to control the growth of two important fungal pathogens, namely Candida auris and species of Cryptococcus. Four of these compounds showed promising antifungal activities.
Keyphrases
  • candida albicans
  • biofilm formation
  • gram negative
  • cell wall
  • pseudomonas aeruginosa
  • staphylococcus aureus
  • multidrug resistant