Acute arthritis, skin rash and Lofgren's syndrome.
Ajay ChauhanAditya JandialKundan MishraRajeev SandalPublished in: BMJ case reports (2021)
Sarcoidosis is an autoimmune multisystem granulomatous disorder of unknown aetiology, which mainly affects the adults in the age group of 20-39 years. The disease can affect any organ in the body but mainly presents as bilateral hilar lymphadenopathy, pulmonary infiltrates, cutaneous lesions, ocular manifestations and arthropathy. Lofgren's syndrome is an uncommon initial presentation of sarcoidosis which is recognised by the classical triad of acute arthritis, erythema nodosum and bilateral hilar lymphadenopathy. We describe a newly diagnosed case of sarcoidosis who presented as Lofgren's syndrome. Acute sarcoid arthritis should be kept as one of the differential diagnoses for patients presenting with acute arthritis and skin lesions; and chest X-ray should be considered to rule out bilateral hilar lymphadenopathy in these patients. Early suspicion and identification of classical clinical features are essential to establish early diagnosis.
Keyphrases
- liver failure
- newly diagnosed
- case report
- respiratory failure
- rheumatoid arthritis
- drug induced
- aortic dissection
- high resolution
- pulmonary hypertension
- ejection fraction
- chronic kidney disease
- computed tomography
- soft tissue
- interstitial lung disease
- wound healing
- magnetic resonance
- systemic sclerosis
- mechanical ventilation
- patient reported outcomes
- acute respiratory distress syndrome