Hypothermic storage of leukoreduced red blood cells for greater than 21 days is a safe alternative to irradiation.

Olga MykhailovaTracey R TurnerCarly OlafsonAnita HowellSusan N NahirniakJuanita WizniakHanan Y N GergesTroy BaldwinGwen ClarkeJason P Acker

Published in: Transfusion (2021)

Hypothermic storage of RBCs for 21 days or more is sufficient to inactivate T lymphocytes, which may help prevent TA-GVHD when irradiated RBCs are not available.

Keyphrases

red blood cell
allogeneic hematopoietic stem cell transplantation
radiation induced
acute lymphoblastic leukemia
acute myeloid leukemia