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Before and after: craving, mood, and background stress in the hours surrounding drug use and stressful events in patients with opioid-use disorder.

Kenzie L PrestonWilliam J KowalczykKarran A PhillipsMichelle L JobesMassoud VahabzadehJia-Ling LinMustapha MezghanniDavid H Epstein
Published in: Psychopharmacology (2018)
Stress increased before stressful-event entries, but was less evident before drug use. Craving increased in the hours before drug use and stressful events-and remained elevated in the hours after either event. These results suggest a stronger link between drug use and craving than between drug use and stress. Lapses to drug use did not improve mood or reduce stress, at least not at our 1-h-bin time resolution, suggesting that if such benefits exist, they are brief.
Keyphrases
  • bipolar disorder
  • stress induced
  • heat stress
  • physical activity
  • single molecule