Beta 2 Adrenergic Receptor Genetic Polymorphisms in Bronchial Asthma: Relationship to Disease Risk, Severity, and Treatment Response.

Aliaë A R Mohamed-HusseinSuzan S SayedHeba M Saad EldienAzza M AssarFatma E Yehia

Published in: Lung (2018)

The findings suggest that the Arg16Gly and Gln27Glu polymorphisms in the β2-AR gene are associated with asthma severity and response to therapy and might be used in personalized treatment for these patients in the future. This work is registered in ClinicalTrial.gov with ID: NCT03118869.

Keyphrases

chronic obstructive pulmonary disease
end stage renal disease
lung function
ejection fraction
peritoneal dialysis
gene expression
prognostic factors
stem cells
genome wide
copy number
dna methylation
patient reported outcomes
cystic fibrosis
combination therapy
air pollution
bone marrow
binding protein