Irisin reduces orthodontic tooth movement in rats by promoting the osteogenic potential in the periodontal ligament.
Yang YangHelen PullisaarAstrid Kamilla StunesLiebert Parreiras NogueiraUnni SyversenJanne Elin ReselandPublished in: European journal of orthodontics (2023)
Submucosal irisin injection reduced OTM by enhancing osteogenic potential of PDL, and this effect was more significant on the compression side.