The glycocalyx core protein Glypican 1 protects vessel wall endothelial cells from stiffness-mediated dysfunction and disease.
Marwa MahmoudMariya MayerLimary M CancelAnne Marie BartoschRick MathewsJohn M TarbellPublished in: Cardiovascular research (2022)
Arterial stiffness promotes EC dysfunction and vascular disease at least partly through the suppression of the glycocalyx protein Glypican 1. Glypican 1 contributes to the protection against endothelial cell dysfunction and vascular disease in endothelial cells.