Analysis of sex-based differences in clinical and molecular responses to ischemia reperfusion after lung transplantation.
Lourdes Chacon-AlbertyShengbin YeDaoud DaoudWilliam C FrankelHassan VirkJonathan MaseCamila Hochman-MendezMeng LiLuiz C SampaioDoris A TaylorGabriel LoorPublished in: Respiratory research (2021)
Men and women differ in the evolution of PGD and cytokine secretion after LTx: Women have a more sustained proinflammatory response than men despite a greater reduction in PGD over time. This interaction between cytokine and PGD responses warrants investigation. Additionally, there may be important sex-related differences that could be used to tailor treatment during or after transplantation.