Low serum uric acid levels are associated with the nonmotor symptoms and brain gray matter volume in Parkinson's disease.

Xiaoxue ShiJinhua ZhengJian Jun MaZhidong WangWenhua SunMingjian LiShen HuangShiyu Hu

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2021)

This study shows that serum UA levels were correlated with the nonmotor symptoms of dysphagia, anxiety, depression, apathy, and cognitive dysfunction and the whole-brain gray matter volume. That is the first report examining the relationships between serum UA and clinical manifestations and imaging features in PD patients.

Keyphrases

uric acid
sleep quality
parkinson disease
end stage renal disease
metabolic syndrome
white matter
resting state
ejection fraction
chronic kidney disease
high resolution
depressive symptoms
prognostic factors
multiple sclerosis
physical activity
deep brain stimulation
subarachnoid hemorrhage