Login / Signup

A novel synthesis, X-ray analysis and computational studies of (Z)-ethyl 2-((Z)-5-((dimethylamino)methylene)- 4-oxo-3-phenylthiazolidin-2-ylidene)acetate as a potential anticancer agent.

Yahia Nasser MabkhotMohammed M AlharbiSalim S Al-ShowimanSaied M SolimanNabila A KhederWolfgang FreyAbdulrhman AsayariAbdullatif Bin MuhsinahH Algarni
Published in: BMC chemistry (2019)
An unexpected synthesis of (Z)-ethyl 2-((Z)-5-((dimethylamino)methylene)-4-oxo-3-phenylthiazolidin-2-ylidene)acetate via deacetylation mechanism. The structure was established using X-ray and spectral analysis. The geometric parameters, and NMR spectra were discussed. The synthesized compounds showed moderate anticancer activity.
Keyphrases
  • high resolution
  • dual energy
  • magnetic resonance
  • ionic liquid
  • optical coherence tomography
  • computed tomography
  • high intensity
  • climate change
  • solid state
  • case control