Susceptibility to preoperative seizures in glioma patients with elevated homocysteine levels.
Xiaohan ChiJingjing LuZhengguang GuoJunmei WangGaifen LiuZeping JinYi WangQianhe ZhangTai SunNan JiYang ZhangPublished in: Epilepsia open (2023)
Glioma patients with hyperhomocysteinemia and the MTHFR C677T variant were susceptible to preoperative seizures, suggesting their potential as biomarkers for the management of seizures in glioma patients. The elevation of intratumoral Hcy is a possible mechanism underlying this susceptibility.