Renin angiotensin system molecules and chemokine (C-C motif) ligand 2 (CCL2) in chronic kidney disease patients.

Isabella Viana Gomes SchettiniDébora Vargas FariaLeilismara Sousa NogueiraAlba Otoni Ana Cristina Dos Santos LopesDanyelle Romana Alves Rios

Published in: Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia (2021)

Patients with CKD showed greater activity of both RAAS axes, the classic and alternative, and higher plasma levels of CCL2. Therefore, plasma levels of RAAS molecules and CCL2 seem to be promising prognostic markers and even therapeutic targets for CKD.

Keyphrases

chronic kidney disease
end stage renal disease
liver fibrosis
liver injury
ejection fraction
newly diagnosed
peritoneal dialysis