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Single-Cell Molecular Characterization to Partition the Human Glioblastoma Tumor Microenvironment Genetic Background.

Francesca LessiSara FranceschiMariangela MorelliMichele MenicagliFrancesco PasqualettiOrazio SantonocitoCarlo GambaccianiFrancesco PieriFilippo AquilaPaolo AretiniChiara Maria Mazzanti
Published in: Cells (2022)
Nowadays, single-cell approaches are leading to a new understanding of GB physiology and disease. Moreover, single-cell CNAs resource will permit new insights into genome heterogeneity, mutational processes, and clonal evolution in malignant tissues.
Keyphrases
  • single cell
  • rna seq
  • high throughput
  • endothelial cells
  • genome wide
  • gene expression
  • induced pluripotent stem cells
  • dna methylation
  • copy number