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Analysis of maternal Fc gamma receptor IIIb isoantibodies using immunomagnetic negative selected neutrophils.

Juliana Oliveira MartinsElyse MoritzSamira Ali AbbasBehnaz BayatMelca Maria Oliveira BarrosRenato de MarcoRenata Fantini MachadoJosé Orlando Bordin
Published in: Vox sanguinis (2024)
Two cases of maternal anti-FcγRIIIb isoantibodies, unrelated to NAIN, were identified. Although neutropenia has not been described in these cases, we emphasize the importance of identifying asymptomatic cases with the potential for severe neutropenia. Additionally, IMNS is introduced as a rapid, high-yield, high-purity neutrophil isolation technique, beneficial for serological assays detecting anti-HNA antibodies.
Keyphrases
  • birth weight
  • pregnancy outcomes
  • early onset
  • high throughput
  • pregnant women
  • risk assessment
  • physical activity
  • single cell