Elevated leptin levels induce inflammation through IL-6 in skeletal muscle of aged female rats.
Ryo TazawaKentaro UchidaHisako FujimakiMasayuki MiyagiGen InoueHiroyuki SekiguchiKosuke MurataKen TakataAyumu KawakuboMasashi TakasoPublished in: BMC musculoskeletal disorders (2019)
Our results suggest that elevated leptin levels due to aging cause ectopic inflammation through IL-6 in the skeletal muscle of aged rats.