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Epigenome-wide association study of total serum immunoglobulin E in children: a life course approach.

Cheng PengAndres CardenasSheryl L Rifas-ShimanMarie-France HivertDiane R GoldThomas A Platts-MillsXihong LinEmily OkenAndrea A BaccarelliAugusto A LitonjuaDawn L DeMeo
Published in: Clinical epigenetics (2018)
This study identified fetally programmed and mid-childhood methylation signals associated with mid-childhood IgE. Epigenetic priming during fetal development and early childhood likely plays an important role in IgE-mediated type-I hypersensitivity.
Keyphrases
  • dna methylation
  • gene expression
  • young adults
  • genome wide
  • early life
  • childhood cancer