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Acute alcohol withdrawal and recovery in men lead to profound changes in DNA methylation profiles: a longitudinal clinical study.

Stephanie-H WittJosef FrankUlrich FrischknechtJens TreutleinFabian StreitJerome C FooLea SirignanoHelene DukalFranziska DegenhardtAnne KoopmannSabine HoffmannGabi KollerOliver PogarellUlrich W PreussPeter ZillKristina AdorjanThomas G SchulzeMarkus NöthenRainer SpanagelFalk KieferMarcella Rietschel
Published in: Addiction (Abingdon, England) (2020)
Acute alcohol withdrawal in severely dependent male patients appears to be associated with extensive changes in epigenome-wide methylation patterns. In particular, genes involved in immune system response seem to be affected by this condition.
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