The -514C>T polymorphism in the LIPC gene modifies type 2 diabetes risk through modulation of HDL-cholesterol levels in Mexicans.
M T Guerra-GarcíaH Moreno-MacíasA Ochoa-GuzmánM L Ordoñez-SánchezR Rodríguez-GuillenP Vázquez-CárdenasV M Ortíz-OrtegaM Peimbert-TorresC A Aguilar-SalinasMaría Teresa Tusié-LunaPublished in: Journal of endocrinological investigation (2020)
The -514C>T polymorphism was not directly associated with T2D risk. HDL-C acts as a mediator between -514C>T LIPC gene variant and T2D risk in the Mexican population.