Highly Sensitive and Selective Fluorescence "Turn-On" Detection of Pb (II) Based on Fe3O4@Au-FITC Nanocomposite.
Yina CaiBinxue RenChi-Fang PengCunzheng ZhangXinlin WeiPublished in: Molecules (Basel, Switzerland) (2021)
New nanocomposites, Fe3O4@Au-FITC, were prepared and explored to develop a fluorescent detection of Pb2+. The Fe3O4@AuNPs-FITC nanocomposites could be etched by Pb2+ in the presence of Na2S2O3, leading to fluorescence recovery of FITC quenched by Fe3O4@Au nanocomposites. With the increase of Pb2+ concentration, the fluorescence recovery of Fe3O4@AuNPs-FITC increased gradually. Under optimized conditions, a detection limit of 5.2 nmol/L of Pb2+ with a linear range of 0.02-2.0 µmol/L were obtained. The assay demonstrated negligible response to common metal ions. Recoveries of 98.2-106.4% were obtained when this fluorescent method was applied in detecting Pb2+ spiked in a lake-water sample. The above results demonstrated the high potential of ion-induced nanomaterial etching in developing robust fluorescent assays.
Keyphrases
- heavy metals
- reduced graphene oxide
- label free
- quantum dots
- aqueous solution
- sensitive detection
- living cells
- loop mediated isothermal amplification
- single molecule
- visible light
- energy transfer
- carbon nanotubes
- gold nanoparticles
- risk assessment
- real time pcr
- fluorescent probe
- high throughput
- high glucose
- mass spectrometry
- stress induced
- human health