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MYDGF attenuates podocyte injury and proteinuria by activating Akt/BAD signal pathway in mice with diabetic kidney disease.

Mingjuan HeYixiang LiLi WangBei GuoWen MeiBiao ZhuJiajia ZhangYan DingBiying MengLiming ZhangLin XiangJing DongMin LiuLingwei XiangGuangda Xiang
Published in: Diabetologia (2020)
The study demonstrates that MYDGF protects podocytes from injury and prevents the progression of DKD, providing a novel strategy for the treatment of DKD. Graphical abstract.
Keyphrases
  • signaling pathway
  • diabetic nephropathy
  • high glucose
  • type diabetes
  • cell proliferation
  • high fat diet induced
  • mouse model
  • wound healing
  • combination therapy
  • adipose tissue
  • metabolic syndrome
  • smoking cessation