Evaluation of post-thaw CFU-GM: clinical utility and role in quality assessment of umbilical cord blood in patients receiving single unit transplant.
Eiman A HusseinTodd DeForJohn E WagnerDarin SumstadClaudio G BrunsteinDavid H McKennaPublished in: Transfusion (2019)
Post-thaw CFU-GM is an effective measure of the quality and efficacy of the UCB graft, particularly adding valuable clinical information when the CD34+ cell dose is low. Consideration of pre-freeze CD34+ cell content and CBB as additional selection criteria is warranted.