Local nebulization of 1α,25(OH) 2 D 3 attenuates LPS-induced acute lung inflammation.

Jef SerréCarolien MathyssenTom Tanjeko AjimeTobias HeiglLieve VerlindenKaren MaesAnnemieke VerstuyfDidier CataldoJeroen VanoirbeekBart VanaudenaerdeWim JanssensGhislaine Gayan-Ramirez

Published in: Respiratory research (2022)

nebulization failed to significantly minimize cellular inflammation in BAL at this dose, it prevented epithelial barrier leakage and damage in lung. Additional research is needed to determine the potential long-term beneficial effects of local 1α,25(OH)2D3 nebulization on lung inflammation.

Keyphrases

oxidative stress
inflammatory response
risk assessment
anti inflammatory
climate change
human health