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High performance methylated DNA markers for detection of colon adenocarcinoma.

Romy A M Klein KranenbargAbdul Hussain ValiJan N M IJzermansThomas R PisanicTza-Huei WangNilofer AzadSaraswati SukumarMary Jo Fackler
Published in: Clinical epigenetics (2021)
We identified high performance methylated DNA marker panels for detection of CC. This knowledge has set the stage for development and implementation of novel, automated, self-contained CC detection assays in tissue and blood which can expeditiously and accurately detect colon cancer in both developed and underdeveloped regions of the world, enabling optimal use of limited resources in low- and middle-income countries.
Keyphrases
  • loop mediated isothermal amplification
  • healthcare
  • real time pcr
  • label free
  • circulating tumor
  • high throughput
  • primary care
  • single molecule
  • cell free
  • squamous cell carcinoma
  • machine learning