Multinucleated stromal giant cells in the gastroesophageal junctional and gastric mucosa: a retrospective study.

Taha SachakWendy L FrankelChristina A ArnoldHui-Zi Chen

Published in: Diagnostic pathology (2019)

MSGCs in the esophagogastric mucosa show smooth muscle/myofibroblast differentiation by immunohistochemistry and likely represent a reactive/reparative stromal reaction associated with gastroesophageal reflux and reactive (chemical) gastropathy.

Keyphrases

smooth muscle
bone marrow
induced apoptosis
cell cycle arrest
transforming growth factor
endoplasmic reticulum stress
oxidative stress
cell death
cell proliferation
pi k akt
electron transfer