Photoactive Liposomal Formulation of PVP-Conjugated Chlorin e6 for Photodynamic Reduction of Atherosclerotic Plaque.
Wojciech KałasEdyta WysokińskaMagdalena PrzybyłoMarek LangnerAgnieszka Ulatowska-JarżaDariusz BiałyMagdalena WawrzyńskaEwa ZiołoWojciech GilAnna M TrzeciakHalina PodbielskaMarta KopaczyńskaPublished in: International journal of molecular sciences (2019)
Due to the excellent physical and pharmacokinetic properties and selectivity for macrophages, the novel liposomal formulation of Photolon is a promising therapeutic candidate for use in arteriosclerosis treatment when targeting macrophages but not accompanying vascular tissue is critical for effective and safe therapy.