High alkaline phosphatase and low intact parathyroid hormone associate with worse clinical outcome in peritoneal dialysis patients.

Zhimin ChenXiaohui ZhangFei HanXishao XieZhou HuaXiaohan HuangBengt LindholmMathias HaarhausPeter StenvinkelAbdul Rashid QureshiJianghua Chen

Published in: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis (2020)

The combination of high ALP and low iPTH was independently associated with increased all-cause and cardiovascular mortality in PD patients, suggesting that ALP and iPTH have the potential to predict clinical outcomes and might be useful risk assessment tools in PD patients. Further studies exploring the observed association between combination of ALP with iPTH and mortality are warranted.

Keyphrases

end stage renal disease
peritoneal dialysis
chronic kidney disease
ejection fraction
risk assessment
newly diagnosed
prognostic factors
cardiovascular disease
cardiovascular events
patient reported outcomes