Evaluating adipose-derived stem cell exosomes as miRNA drug delivery systems for the treatment of bladder cancer.

Tianyao LiuTianhang LiYufeng ZhengXinyan XuRui SunShoubin ZhanXu GuoZihan ZhaoWenjie ZhuBaofu FengFayun WeiNing JiangJin WangXi ChenFeng FangHong-Qian GuoRong Yang

Published in: Cancer medicine (2022)

The present results reveal that ADSC-derived exosomes are an effective delivery vehicle for small molecule drugs in vivo, and exosome-delivered miR-138-5p is a promising therapeutic agent for BC treatment.

Keyphrases

stem cells
small molecule
mesenchymal stem cells
single cell
combination therapy
bone marrow
replacement therapy
cell therapy