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Feasibility of feeding Aedes aegypti mosquitoes on dengue virus-infected human volunteers for vector competence studies in Iquitos, Peru.

Kanya C LongJuan SulcaIsabel BazanHelvio AsteteHugo L JabaCrystyan SilesClaudine KocherStalin VilcarromeroJulia SchwarzKarin S Escobedo-VargasFanny Castro-LlanosLeslye AnguloGuadalupe FloresCesar Ramal-AsayagEric S HalseyRobert D HontzValerie A Paz-SoldanThomas W ScottLouis LambrechtsAmy C Morrison
Published in: PLoS neglected tropical diseases (2019)
Our study demonstrates the feasibility of using direct and indirect feeding methods for field-based studies on vector competence. Direct mosquito feeding is preferable in terms of logistical ease, biosecurity, and reliability.
Keyphrases
  • aedes aegypti
  • dengue virus
  • zika virus
  • case control
  • endothelial cells
  • induced pluripotent stem cells