Pulsatile corticoid therapy reduces interictal epileptic activity burden in children with genetic drug-resistant epilepsy.
Katharina SchillerJohn ThomasTamir AvigdorDaniel MansillaAline KortasGabriele UnterholznerMarkus RauchenzaunerBirgit FrauscherPublished in: Epilepsia open (2024)
In this study, children with a form of epilepsy, which is resistant against antiseizure medication, received a systematic treatment with corticosteroids over multiple cycles in the hospital. It was found that not only the epileptic activity was reduced but also the sleep of the patients was improved after the treatment. These findings could provide the basis for extending the use of corticosteroids in children with epilepsy.
Keyphrases
- drug resistant
- young adults
- end stage renal disease
- multidrug resistant
- healthcare
- ejection fraction
- chronic kidney disease
- acinetobacter baumannii
- stem cells
- peritoneal dialysis
- emergency department
- adverse drug
- prognostic factors
- genome wide
- dna methylation
- pseudomonas aeruginosa
- temporal lobe epilepsy
- combination therapy
- risk factors
- mesenchymal stem cells
- cell therapy