Elevated serum gasdermin D N-terminal implicates monocyte and macrophage pyroptosis in adult-onset Still's disease.

Hideto NagaiYohei KirinoHiroto NakanoYosuke KunishitaRiko HenmiAnn Marie SzymanskiRyusuke YoshimiMichael J OmbrelloHideaki Nakajima

Published in: Rheumatology (Oxford, England) (2021)

Elevation of serum gasdermin D N-terminal provides evidence for inflammasome activation triggering gasdermin D-mediated Mo and Mφ pyroptosis in AOSD and possibly sJIA.

Keyphrases

nlrp inflammasome
dendritic cells
endothelial cells
peripheral blood
immune response