Impact of peri-intraventricular haemorrhage and periventricular leukomalacia in the neurodevelopment of preterms: A systematic review and meta-analysis.
Juliana Wendling GotardoNathalia de Freitas Valle VolkmerGuilherme Pucci StanglerAlícia Dorneles DornellesBetânia Barreto de Athayde BohrerClarissa Gutiérrez CarvalhoPublished in: PloS one (2019)
There was no evidence supporting the hypothesis that PIVH causes impairment in neuropsychomotor development in our meta-analysis, but review of newer studies show an increased risk for lower intelligence scores in children with severe lesions, both PIVH and PVL. There is evidence to support the hypothesis that children with any degree of PIVH, especially those born below 1000 grams and those with severe haemorrhage, are at increased risk of developing CP, as well as children with PVL, both cystic and non-cystic.