Continuous chest compressions with asynchronous ventilations increase carotid blood flow in the perinatal asphyxiated lamb model.
Payam ValiAmy LesneskiMorgan HardieZiad AlhassenPeggy ChenHoussam JoudiDeepika SankaranSatyan LakshminrusimhaPublished in: Pediatric research (2021)
In a perinatal asphyxiated cardiac arrest lamb model, CCCaV improved carotid blood flow and oxygen delivery to the brain compared to the conventional 3:1 C:V resuscitation. Pre-clinical studies assessing neurodevelopmental outcomes and tissue injury comparing continuous uninterrupted chest compressions to the current recommended 3:1 C:V during newborn resuscitation are warranted prior to clinical trials.
Keyphrases
- blood flow
- cardiac arrest
- cardiopulmonary resuscitation
- clinical trial
- pregnant women
- resting state
- metabolic syndrome
- adipose tissue
- septic shock
- multiple sclerosis
- insulin resistance
- type diabetes
- atrial fibrillation
- venous thromboembolism
- phase ii
- brain injury
- glycemic control
- functional connectivity
- subarachnoid hemorrhage
- congenital heart disease